The role of malignancy in the mortality of Stevens-Johnson syndrome and toxic epidermal necrolysis
نویسندگان
چکیده
Background Stevens-Johnson syndrome (SJS) / Toxic epidermal necrolysis (TEN) is a rare, severe, and occasionally fatal skin reaction caused mainly by medications. The reported mortality associated with TEN varies from 10-70%. SCORTEN, a severity-of-illness score which estimates the mortality in TEN has been developed and validated. Malignancy was considered as 1 of the 7 independent prognostic factors of SCORTEN. However, the studies focused on the associated factors of malignancy in the mortality of SJS/TEN were limited. In this study, we tried to analyze the true role of malignancy in the mortality of SJS/TEN.
منابع مشابه
Survey on Etiology of Stevens-Johnson syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Six-Year Study from Iran
Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are among the most severe dermatologic reactions to the drugs. Data about SJS and TEN among pediatric population especially in Iran is limited. This study aimed to investigate the clinical and para-clinical characteristics of pediatric patients with SJS/TEN. Materials and Methods From 2010 to 2016, all SJS and TEN c...
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